Conjoined twins are two babies who are born physically connected to each other.
Conjoined twins develop when an early embryo only partially separates to form two individuals. Although two babies develop from this embryo, they remain physically connected — most often at the chest, abdomen or pelvis. Conjoined twins may also share one or more internal body organs.
Though many conjoined twins are not alive when born (stillborn) or die shortly after birth, advances in surgery and technology have improved survival rates. Some surviving conjoined twins can be surgically separated. The success of surgery depends on where the twins are joined and how many and which organs are shared. It also depends on the experience and skill of the surgical team.
There are no specific symptoms that indicate a conjoined twin pregnancy. As with other twin pregnancies, the uterus may grow faster than it does with a single baby. And there may be more tiredness, nausea and vomiting early in the pregnancy. Conjoined twins can be diagnosed early in the pregnancy using an ultrasound.
Conjoined twins are usually classified according to where they're joined. The twins sometimes share organs or other parts of their bodies. Each pair of conjoined twins is unique.
Conjoined twins may be joined at any of these sites:
In rare cases, twins may be conjoined with one twin smaller and less fully formed than the other (asymmetric conjoined twins). In extremely rare cases, one twin may be found partially developed within the other twin (fetus in fetu).
Identical twins (monozygotic twins) occur when a single fertilized egg splits and develops into two individuals. Eight to 12 days after conception, the embryonic layers that split to form monozygotic twins begin to develop into specific organs and structures.
It's believed that when the embryo splits later than this — usually between 13 and 15 days after conception — separation stops before the process is complete. The resulting twins are conjoined.
An alternative theory suggests that two separate embryos may somehow fuse together in early development.
What might cause either chain of events to occur is unknown.
Because conjoined twins are so rare, and the cause isn't clear, it's unknown what might make some couples more likely to have conjoined twins.
Pregnancy with conjoined twins is complex and greatly increases the risk of serious complications. Conjoined babies require surgical delivery by cesarean section (C-section).
As with twins, conjoined babies are likely to be born prematurely, and one or both could be stillborn or die shortly after birth. Severe health issues for twins can occur immediately, such as trouble breathing or heart problems. Later in life, health issues such as scoliosis, cerebral palsy or learning disabilities may occur.
Possible complications depend on where the twins are joined, which organs or other parts of the body they share, and the expertise and experience of the health care team. When conjoined twins are expected, the family and the health care team need to discuss in detail the possible complications and how to prepare for them.
Conjoined twins can be diagnosed using routine ultrasound as early as 7 to 12 weeks of pregnancy. More-detailed ultrasounds and tests that use sound waves to produce images of the babies' hearts (echocardiograms) can be used about halfway through pregnancy. These tests can better determine the extent of the twins' connection and the functioning of their organs.
If an ultrasound detects conjoined twins, a magnetic resonance imaging (MRI) scan may be done. The MRI may provide greater detail about where the conjoined twins are connected and which organs they share. Fetal MRI and fetal echocardiography assist with planning for care during and after pregnancy. After birth, other tests are done to help identify the body structure and organ function of each twin and what is shared.
Treatment of conjoined twins depends on their unique situation — their health issues, where they're joined, whether they share organs or other vital structures, and other possible complications.
If you're carrying conjoined twins, you'll likely be closely monitored throughout your pregnancy. You'll likely be referred to a maternal and fetal medicine specialist in high-risk pregnancy. When needed, you may also be referred to other pediatric specialists in:
Your specialists and others on your health care team learn as much as possible about your twins. This includes learning about their body structures, their ability to perform certain activities (functional capabilities) and the likely outcome (prognosis) to form a treatment plan for your twins.
A C-section is planned ahead of time, often 3 to 4 weeks before your due date.
After your conjoined twins are born, they're fully evaluated. With this information, you and your health care team can make decisions regarding their care and whether separation surgery is appropriate.
If a decision is made to separate the twins, separation surgery is usually done around 6 to 12 months after birth to allow time for planning and preparation. Sometimes an emergency separation may be needed if one of the twins dies, develops a life-threatening condition or threatens the survival of the other twin.
Many complex factors must be considered as part of the decision to do separation surgery. Each set of conjoined twins presents a unique set of issues due to differences in body structure and function. Issues include:
Recent advances in imaging before birth, critical care and anesthetic care have improved outcomes in separation surgery. After separation surgery, pediatric rehabilitation services are crucial to help the twins develop properly. Services may include physical, occupational and speech therapies and other assistance as needed.
If separation surgery isn't possible or if you decide not to have the surgery done, your team can help you meet the medical care needs of your twins.
If the circumstances are grave, medical comfort care — such as nutrition, fluids, human touch and pain relief — is provided.
Learning that your unborn twins have a major medical issue or life-threatening condition can be devastating. As a parent, you struggle with difficult decisions for your conjoined twins and the uncertain future. Outcomes can be difficult to determine, and conjoined twins who survive sometimes face tremendous obstacles.
Because conjoined twins are rare, it may be difficult to find supportive resources. Ask your health care team if medical social workers or counselors are available to help. Depending on your needs, ask for information on organizations that support parents who have children with physical conditions that limit their abilities or who have lost children.
If you're pregnant with conjoined twins, you'll be referred to a team of specialists to help guide you and create a treatment plan for your twins. Here's some information to help you get ready and what to expect from your team.
Before your appointment:
Some basic questions to ask include:
Don't hesitate to ask other questions during your appointment.
Your health care provider and other members of your health care team review your conjoined twins' tests and exam results and discuss options with you. Together with your team, you can make decisions for your twins' treatment and care.
